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Physician Assistant vs Registered Nurse: what changes?

Consider Physician Assistant if you want to provide healthcare services typically performed by a physician, under the supervision of a physician. Consider Registered Nurse if you would rather assess patient health problems and needs, develop and implement nursing care plans, and maintain medical records. Entry credentials differ: Physician Assistant, master's degree; Registered Nurse, associate degree or approved diploma; bachelor's route also available.

Try this next: Compare three local entry-level postings for Physician Assistant and Registered Nurse. List the duties, credentials, prior experience, and paid training each employer actually asks for. Try a supervised class or sample project from each field before choosing a program.

BLS 2025 wages and 2025–2035 projections. National medians are not starting offers. Occupation size is not a count of vacancies. View the BLS data.

Compare the practical differences
What this means in practice

The facts most likely to affect your decision

Start with earnings, the route into the job, training, available openings, and a day-to-day reality.

Physician Assistant

National median pay (2025)
$135,880
Route into the job
Master's degree
Prior related experience
No prior related occupation is typically required; employer requirements vary.
Training and licensing
BLS does not list a separate on-the-job training requirement. Employers may still provide orientation and role-specific training.
Work to investigate
Make tentative diagnoses and decisions about management and treatment of patients.
Annual openings (2025–2035)
11,500
Know before you choose

Exposure to illness or infection is a recurring part of the work context, even when safety procedures are followed.

See the full Physician Assistant brief

Registered Nurse

National median pay (2025)
$97,550
Route into the job
Bachelor's, associate-degree, and approved diploma routes exist, followed by licensure. A BSN typically takes four years; compare prerequisites and clinical placements for the full timeline. Some employers require a BSN.
Prior related experience
No prior related occupation is typically required; employer requirements vary.
Training and licensing
BLS does not list a separate on-the-job training requirement. Employers may still provide orientation and role-specific training.
Physical work
Standing, walking, bending, and patient handling; demands depend on the care setting.
Schedule and hours
Hospital work may include nights, weekends, holidays, and on-call coverage. Office and school roles more often have regular hours.
Annual openings (2025–2035)
180,800
Know before you choose

A shortage does not guarantee a well-staffed unit. Ask about patient assignments, orientation, turnover, and shift expectations.

BLS: entry routes, workplace, and schedules · Reviewed September 6, 2026. BLS 2025 wages and 2025–2035 projections.

What the workforce research adds

The retention warning is serious: 39.9%. Share of RNs reporting intent to leave the nursing workforce or retire within five years.

NCSBN National Nursing Workforce Study · 2024. Survey measures differ across careers; their percentages are not directly comparable. A national survey does not establish local hiring odds or the quality of a particular employer.

See the full Registered Nurse brief
See scores, detailed data, and how the comparison works

How the national numbers differ

1

Registered Nurse has the edge on annual openings

Registered Nurse is at 180,800 annual openings, compared with 11,500 annual openings for Physician Assistant.

2

Physician Assistant has the edge on projected growth

Physician Assistant is at 21.1% projected growth, compared with 5.6% projected growth for Registered Nurse.

3

Physician Assistant has the edge on median pay

Physician Assistant is at $135,880, compared with $97,550 for Registered Nurse.

4

Typical preparation differs.

Physician Assistant: Master's degree Registered Nurse: Bachelor's, associate-degree, and approved diploma routes exist, followed by licensure. A BSN typically takes four years; compare prerequisites and clinical placements for the full timeline. Some employers require a BSN. Preparation categories do not establish admission difficulty, calendar time, tuition, time without earnings, or licensing difficulty.

74.2/ 100

Physician Assistant

vs
76.5/ 100

Registered Nurse

Each available metric is ranked from 0 to 100 against the careers on ChooseField. The weighted average uses this profile: pay 30%, growth 25%, openings 30%, preparation level 15%. Missing values are not scored as zero; their weights are redistributed across available metrics. Occupation size has zero weight: employment is not accessible vacancies. Preparation categories do not measure admission difficulty or years without earnings. The score summarizes national measures; local opportunities and personal fit still need separate consideration.

Detailed evidence

Physician Assistant vs Registered Nurse

DimensionPhysician AssistantRegistered Nurse
Median pay (2025)$135,880$97,550
Pay percentile93.3 percentile80.9 percentile
Projected growth (2025–2035)21.1%5.6%
Annual openings (2025–2035)11,500180,800
2025 employment168,9003,465,400
How you qualifyMaster's degreeBachelor's, associate-degree, and approved diploma routes exist, followed by licensure. A BSN typically takes four years; compare prerequisites and clinical placements for the full timeline. Some employers require a BSN.
O*NET preparation groupJob Zone 5Job Zone 4
Related work experienceNo prior related occupation is typically required; employer requirements vary.No prior related occupation is typically required; employer requirements vary.
On-the-job trainingBLS does not list a separate on-the-job training requirement. Employers may still provide orientation and role-specific training.BLS does not list a separate on-the-job training requirement. Employers may still provide orientation and role-specific training.
SchedulesVaries by employer and setting; ask about shifts, overtime, on-call work, and predictable hours.Hospital work may include nights, weekends, holidays, and on-call coverage. Office and school roles more often have regular hours.
Physical workUnknown: review standing, lifting, repetitive movement, and posture with a practitioner. No overall physical-demand rating is assigned.Standing, walking, bending, and patient handling; demands depend on the care setting.

The table reports national benchmarks and reviewed work descriptions. It does not rate personal suitability, job security, or physical safety.